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T cells, monocytes, and NK cell counts in peripheral blood from all acalabrutinib-treated patients over time. Absolute counts of CD4+ (A) and CD8+ (B) T cells, CD14+ monocytes (C), and NK cells (CD16+CD56+; D). Cells were measured by flow cytometry. The normal reference range for each subset is shown with dashed lines. All plots include patients being assessed at baseline assessment and the respective visit. P values are from the Wilcoxon signed-rank test. NK, natural killer.
