TABLE 1.
Frequently mentioned potential “routine laboratory” biomarkers.
Potential biomarkers | Material | Age linked processes# | e-score | rc-score* | c-score |
Lymphocytes/WBC [CDC] [PA] | blood/EDTA | Inflammation autoimmune disorders | - | 202 | 2240 |
Insulin | blood/serum | Diabetic state | – | 148 | 1143 |
Glucose/glucose fastened [PA] | blood/glucose monovette | Diabetic state | - | 111 | 1175 |
C-reactive protein (CRP/hsCRP) [IA] [PA] | blood/plasma | Inflammation, cancer, cardiovascular disease | - | 71 | 1146 |
Cholesterol | blood/plasma | Cardiovascular disease | - | 67 | 896 |
Albumin [PA] | blood/plasma | Kidney and liver dysfunction | - | 65 | 1062 |
IL6 [IA] | blood/plasma | Inflammation | - | 58 | 979 |
Tumor necrosis factor alpha (TNFα) [IA] | blood/serum | Inflammation, cancer | – | 51 | 751 |
Hemoglobin [CDC] | blood/EDTA | Anemia, other hematopoietic disorders | - | 39 | 471 |
Insulin-like growth factor 1 (IGF-1) | blood/serum | Metabolic disease | – | 29 | 263 |
LDL-cholesterol | blood/plasma | Cardiovascular disease | - | 24 | 280 |
Triglycerides | blood/plasma | Cardiovascular disease | - | 23 | 498 |
HDL-cholesterol | blood/plasma | Cardiovascular disease | - | 23 | 349 |
Creatinine [PA] | blood/plasma | Kidney dysfunction | - | 19 | 479 |
Monocytes | blood/EDTA | Inflammation | - | 16 | 378 |
Glycated hemoglobin (Hba1c) | blood/EDTA | Diabetic state | - | 13 | 220 |
Cystatin C | blood/plasma | Kidney dysfunction | - | 12 | 142 |
N-terminal prohormone of brain natriuretic peptide (NT-proBNP) | blood/EDTA | Heart failure | - | 10 | 119 |
Alkaline phosphatase [PA] | blood/plasma | Liver damage, bone disorder | - | 9 | 252 |
Hematocrit/RBC [CDC] | blood/EDTA | Anemia | - | 8 | 159 |
D-dimer | blood/citrate monovette | Hypercoagulable state | - | 8 | 91 |
IL8 [IA] | blood/plasma | Inflammation | – | 7 | 164 |
Plasminogen activator inhibitor-1 (PAI1) | blood/EDTA | Prothrombotic state in cancer and other acute phases | – | 6 | 72 |
Bilirubin | blood/plasma | Liver dysfunction | - | 5 | 46 |
Urea | blood/plasma | Renal dysfunction | - | 3 | 137 |
IL15 | blood/plasma | Inflammation | – | 3 | 55 |
Mean corpuscular volume/MCV [CDC] [PA] | blood/EDTA | Anemia, other hematopoietic disorders | - | 2 | 42 |
Mean corpuscular hemoglobin concentration/MCHC [CDC] | blood/EDTA | Anemia, other hematopoietic disorders | - | 2 | 32 |
CD4/CD8 ratio | blood/EDTA | Immune deficiency, autoimmunity | – | 1 | 103 |
C-peptide (preferable to insulin) | blood/serum | Diabetic state | - | 1 | 32 |
IL1-β [IA] | blood/plasma | inflammation | – | 1 | 5 |
* rows are sorted by rc-score. | [IA] = inflammaging | ||||
# frequently mentioned general or disease-linked processes. | [PA] = Phenotypic Age | ||||
[CDC] = complete blood count |