TABLE 4.
Potential biomarkers | Method | Age linked processes# | Domain | e-score | rc-score* | c-score |
Physical capability | ||||||
Grip strength | Physical exam | Mortality, morbidity | Strength | – | 11 | 229 |
Walking speed | Physical exam | Mortality, morbidity | Locomotor function | – | 3 | 106 |
Standing balance | Physical exam | Mortality, morbidity | Balance | – | 1 | 26 |
Timed up and go test | Physical exam | Mortality, morbidity | Locomotor function | – | 0 | 11 |
Organ function | ||||||
Atherosclerotic lesions | IMT, ultrasound | Mortality, CAD | Cardiovascular system | – | 158 | 680 |
Muscle mass | MRI | Mortality, cardiovascular risk | Body composition | – | 81 | 495 |
Systolic blood pressure | Auscultatory method | Mortality, cardiovascular risk | Cardiovascular system | – | 65 | 844 |
Cognitive function | Various | Mortality, morbidity | Brain function | — | 56 | 581 |
Body mass index | Calculated | Mortality CAD | Body composition | – | 24 | 1280 |
Bone density | Bone density test | Mortality, morbidity | Body composition | – | 17 | 84 |
Lung function | Spirometry | Mortality, morbidity | Respiratory system | – | 16 | 84 |
Waist circumference | Tape measure | Mortality, cardiovascular risk | Body composition | – | 3 | 202 |
General well being | ||||||
Health assessments | Questionnaire | Mortality, morbidity | General | – | n.a. | n.a. |
* rows are sorted by c-score. # frequently mentioned general or disease-linked. n.a.: not assigned due to high variation of terminology in literature.