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. 2021 May 5;12(13):3909–3919. doi: 10.7150/jca.55666

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LINC01272, miR-876 and ITGB2 regulated invasion and migration in vitro. For the Transwell assay, HCT116 cells were transfected with si-LINC01272, si-ITGB2, miR-876 mimics and their corresponding controls. a and b, Inhibition of LINC01272 or ITGB2 expression or overexpression of miR-876 impaired the migration and invasion of HCT116 cells. c and d, Wound healing assay showed that down-regulation of LINC01272 or ITGB2 weakened the migration and motility of HCT116 cells. *p <0.05, **p < 0.01 and ***p < 0.001 compared to the control group by Student's t-test.