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. 2021 May 10;12(13):3930–3944. doi: 10.7150/jca.52286

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A subset of 2574 uniquely expressed genes specific to TCGA-ESCC patient tumor tissues was identified. (A) Diagram illustrating the unique and shared subsets of gene expression after overlapping the four datasets from TCGA-ESCC Tissues, CCLE-ESCC Cell Lines, Protein Atlas-Normal Esophagus Tissue and PDX-ESCC Tissues. (B) The top ten significant signaling pathways enriched from the 2574 TCGA-ESCC Unique genes. (C) The corresponding PPI and networks of signaling pathways derived from TCGA-ESCC Unique genes. (D) 293 genes residing within the Olfactory transduction pathway, out of which 290 genes belong to the Olfactory receptor family. (E) The expression landscape of CNGB1 across different Tumor-Normal tissue pairs. (F) The expression of CNGB1 in ESCA and HNSC. (G) The comparison of CNGB1 expression between 80 ESCC samples and 11 normal esophageal tissues. Significance was assessed using the Mann-Whitney test. * indicates p<.05, *** indicates p<.001.

A subset of 2574 uniquely expressed genes specific to TCGA-ESCC patient tumor tissues was identified. (A) Diagram illustrating the unique and shared subsets of gene expression after overlapping the four datasets from TCGA-ESCC Tissues, CCLE-ESCC Cell Lines, Protein Atlas-Normal Esophagus Tissue and PDX-ESCC Tissues. (B) The top ten significant signaling pathways enriched from the 2574 TCGA-ESCC Unique genes. (C) The corresponding PPI and networks of signaling pathways derived from TCGA-ESCC Unique genes. (D) 293 genes residing within the Olfactory transduction pathway, out of which 290 genes belong to the Olfactory receptor family. (E) The expression landscape of CNGB1 across different Tumor-Normal tissue pairs. (F) The expression of CNGB1 in ESCA and HNSC. (G) The comparison of CNGB1 expression between 80 ESCC samples and 11 normal esophageal tissues. Significance was assessed using the Mann-Whitney test. * indicates p<.05, *** indicates p<.001.