Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
FIRRE knockdown represses the proliferation and glycolysis of HCCLM3 cells. (A) shNT or shFIRRE-1/2 was transfected into HCCLM3 cells, and qRT-PCR was performed to analyze FIRRE expression. (B and C) CCK-8 and EdU assays revealed that FIRRE silencing inhibited the proliferation of HCC cells. Original magnification: 200×. (D-F) Silencing of FIRRE decreased glucose consumption, pyruvate production, and lactate production of HCC cells. *P<0.05.
