Table 3.
Subtypes | Cases | GATA1 | GATA2 | GATA3 | GATA4 | GATA5 | GATA6 | ||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
HR (95% CI) | P | HR (95% CI) | P | HR (95% CI) | P | HR (95% CI) | P | HR (95% CI) | P | HR (95% CI) | P | ||
Stage | |||||||||||||
1 | 577 | 1.12 (0.86-1.47) | 0.41 | 0.48 (0.36-0.64) | 2.3e-7 | 0.5 (0.37-0.66) | 5.4e-7 | 1.48 (1.13-1.94) | 0.0043 | 0.42 (0.3-0.59) | 2.0e-7 | 0.39 (0.3-0.52) | 2.1e-11 |
2 | 244 | 1.4 (0.97-2.02) | 0.07 | 0.77 (0.53-1.11) | 0.16 | 0.86 (0.6-1.24) | 0.41 | 1.17 (0.81-1.68) | 0.41 | 0.81 (0.51-1.28) | 0.36 | 0.63 (0.43-0.91) | 0.012 |
3 | 70 | 0.81 (0.47-1.41) | 0.46 | 0.58 (0.33-1) | 0.048 | 0.78 (0.45-1.35) | 0.38 | 0.81 (0.47-1.4) | 0.45 | 0.72 (0.36-1.45) | 0.36 | 0.99 (0.58-1.7) | 0.98 |
4 | 4 | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA |
Grade | |||||||||||||
I | 201 | 1.9 (1.31-2.76) | 5.6e-4 | 0.8 (0.56-1.15) | 0.22 | 0.98 (0.69-1.4) | 0.92 | 0.98 (0.68-1.4) | 0.91 | NA | NA | 1.01 (0.7-1.44) | 0.98 |
II | 310 | 0.94 (0.69-1.29) | 0.71 | 0.74 (0.54-1.01) | 0.061 | 0.83 (0.61-1.14) | 0.25 | 0.82 (0.6-1.13) | 0.22 | NA | NA | 0.97 (0.71-1.32) | 0.84 |
III | 77 | 1.2 (0.62-2.32) | 0.58 | 0.52 (0.27-1.02) | 0.053 | 0.53 (0.27-1.03) | 0.056 | 1.51 (0.78-2.92) | 0.22 | NA | NA | 0.61 (0.32-1.19) | 0.14 |
Smoking history | |||||||||||||
Exclude those never smoked | 820 | 1.43 (1.16-1.76) | 6.9e-4 | 0.66 (0.53-0.81) | 7.9e-5 | 0.75 (0.61-0.93) | 0.0071 | 1.29 (1.05-1.59) | 0.014 | 0.72 (0.47-1.08) | 0.11 | 0.71 (0.57-0.87) | 0.0011 |
Only those never smoked | 205 | 2.46 (1.37-4.42) | 0.0019 | 0.39 (0.21-0.72) | 0.0017 | 0.34 (0.19-0.63) | 0.0003 | 1.22 (0.7-2.12) | 0.49 | 0.44 (0.17-1.12) | 0.077 | 0.41 (0.22-0.74) | 0.0023 |