TABLE 4.

Daily adherence to maintenance therapy over months 4–6 by baseline asthma control test (ACT) total score and by age group, with the difference in arms 1–4 versus arm 5

Months 4–6	Arm 1 (n=87)	Arm 2 (n=88)	Arm 3 (n=88)	Arm 4 (n=88)	Arm 5 (n=86)
Baseline ACT total score: ≤15
n#	28	31	41	29	33
Least squares mean±se %	82.7±4.61	82.4±4.51	75.5±3.99	75.6±4.61	64.5±4.36
CIS arm versus arm 5
Difference %	18.3	18.0	11.0	11.2
95% CI %	7.1–29.5	7.2–28.7	1.0–21.1	0.1–22.2
Baseline ACT total score: 16–19
n#	55	53	43	53	52
Least squares mean±se %	80.7±3.66	74.8±3.45	81.7±3.90	78.5±3.70	72.7±3.76
CIS arm versus arm 5
Difference %	8.0	2.1	9.0	5.8
95% CI %	−0.5 to 16.5	−6.3 to 10.6	0.1 to 17.8	−2.6 to 14.3
Age group: 18–35 years
n#	23	21	21	13	28
Least squares mean±se %	70.1±5.00	58.8±5.12	68.0±5.30	62.3±6.60	56.9±4.78
CIS arm versus arm 5
Difference %	13.2	1.9	11.1	5.5
95% CI %	0.9–25.6	−10.8 to 14.6	−1.4 to 23.6	−9.1 to 20.0
Age group: 36–48 years
n#	20	24	22	28	19
Least squares mean±se %	82.0±5.38	82.3±4.90	74.7±5.05	76.3±4.68	65.6±5.47
CIS arm versus arm 5
Difference %	16.5	16.8	9.1	10.8
95% CI %	2.6–30.3	3.4–30.1	−4.4 to 22.6	−2.1 to 23.7
Age group: 49–58 years
n#	21	21	18	27	13
Least squares mean±se %	85.1±5.30	84.6±5.21	79.2±5.52	82.1±4.70	76.4±6.47
CIS arm versus arm 5
Difference %	8.7	8.2	2.8	5.7
95% CI %	−6.8 to 24.2	−7.1 to 23.5	−13.1 to 18.6	−8.9 to 20.3
Age group: >58 years
n#	19	18	23	14	25
Least squares mean±se %	88.0±5.56	82.8±5.53	91.6±5.05	87.4±6.42	81.6±4.90
CIS arm versus arm 5
Difference %	6.4	1.2	10.0	5.8
95% CI %	−6.9 to 19.7	−12.2 to 14.6	−2.6 to 22.6	−9.1 to 20.6

Arm 1: maintenance data to participants and HCPs; arm 2: maintenance data to participants; arm 3: maintenance and rescue data to participants and HCPs; arm 4: maintenance and rescue data to participants; arm 5: no feedback (control). CIS: connected inhaler system; CI: confidence interval; HCP: healthcare professional. ^#: over months 4–6, n included the number of participants with observed and imputed data.