Table 1. Current Definitions Extracted From the Systematic Review.

Term	Definitions in the existing literature8,9,10,11,12,13,14,15,16,17,18,19,20,21,22,23,24,25,26,27,28,29,30
Nonadherence	No treatment or monitoring visit at least once every 6 or 8 wk Extreme violation of prescribed treatment regimen Nonattendance at every clinic appointment <8 Injections over 12 mo Visits outside of the prescribed window of 28 ± 7 d
Synonyms: noncompliance, absenteeism, and nonattendance
Nonpersistence	Treatment discontinuation before initial 12 mo, study period end, or permanently No treatment or monitoring visit for 4, 6, 12, or 24 mo No follow-up by an ophthalmologist for 3 mo No follow-up within a 12-mo period after receiving at least 1 anti–vascular endothelial growth factor injection
Synonyms: discontinuation, dropout, cessation, and loss to follow-up