Table 1. Baseline Characteristics of Women Who Completed the First Surgery.
Characteristic | No. (%) | P value | ||
---|---|---|---|---|
Total (n = 548) | RRS (n = 394) | RRSO (n = 154) | ||
Age at inclusion, mean (SD), y | 37.2 (3.5) | 36.6 (3.6) | 38.7 (2.9) | <.001 |
BRCA1 | 35.9 (2.9) | 35.3 (3.2) | 37.0 (1.9) | <.001 |
BRCA2 | 38.7 (3.6) | 37.8 (3.5) | 41.5 (2.1) | <.001 |
Age at first surgery, mean (SD), y | 37.5 (3.5) | 36.8 (3.5) | 38.8 (2.9) | <.001 |
BRCA1 | 36.1 (2.9) | 35.5 (3.2) | 37.1 (1.8) | <.001 |
BRCA2 | 38.8 (3.6) | 38.0 (3.5) | 41.5 (2.1) | <.001 |
Type of BRCA pathogenic variant | ||||
BRCA1 | 285 (52.0) | 190 (48.2) | 95 (61.7) | .005 |
BRCA2 | 263 (48.0) | 204 (51.8) | 59 (38.3) | |
Relationship status | ||||
Married/partner | 487 (88.9) | 349 (88.6) | 138 (89.6) | .51 |
Single | 54 (9.9) | 41 (10.4) | 13 (8.4) | |
Unknown | 7 (1.3) | 4 (1.0) | 3 (1.9) | |
Offspring | ||||
No | 62 (11.3) | 46 (11.7) | 16 (10.4) | .72 |
Yes | 476 (86.9) | 343 (87.1) | 133 (86.4) | |
Unknown | 10 (1.8) | 5 (1.3) | 5 (3.2) | |
Educational level | ||||
Low | 62 (11.3) | 45 (11.4) | 17 (11.0) | .98 |
Medium | 194 (35.4) | 139 (35.3) | 55 (35.7) | |
High | 285 (52.0) | 206 (52.3) | 79 (51.3) | |
Unknown | 7 (1.3) | 4 (1.0) | 3 (1.9) | |
Breast cancer in personal history | ||||
No | 462 (84.3) | 331 (84.0) | 131 (85.1) | .58 |
Yes | 79 (14.4) | 59 (15.0) | 20 (13.0) | |
Unknown | 7 (1.3) | 4 (1.0) | 3 (1.9) | |
Risk-reducing mastectomy | ||||
No | 328 (59.9) | 235 (59.6) | 93 (60.4) | .78 |
Yes | 213 (38.9) | 155 (39.3) | 58 (37.7) | |
Unknown | 7 (1.3) | 4 (1.0) | 3 (1.9) | |
First-degree family member with ovarian cancer | ||||
No | 463 (84.5) | 339 (86.0) | 124 (80.5) | .18 |
Yes | 76 (13.9) | 50 (12.7) | 26 (16.9) | |
Unknown | 9 (1.6) | 5 (1.3) | 4 (2.6) |
Abbreviations: RRS, risk-reducing salpingectomy; RRSO, risk-reducing salpingo-oophorectomy.