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. 2021 Jun 3;7(8):1203–1212. doi: 10.1001/jamaoncol.2021.1590

Table 1. Baseline Characteristics of Women Who Completed the First Surgery.

Characteristic No. (%) P value
Total (n = 548) RRS (n = 394) RRSO (n = 154)
Age at inclusion, mean (SD), y 37.2 (3.5) 36.6 (3.6) 38.7 (2.9) <.001
BRCA1 35.9 (2.9) 35.3 (3.2) 37.0 (1.9) <.001
BRCA2 38.7 (3.6) 37.8 (3.5) 41.5 (2.1) <.001
Age at first surgery, mean (SD), y 37.5 (3.5) 36.8 (3.5) 38.8 (2.9) <.001
BRCA1 36.1 (2.9) 35.5 (3.2) 37.1 (1.8) <.001
BRCA2 38.8 (3.6) 38.0 (3.5) 41.5 (2.1) <.001
Type of BRCA pathogenic variant
BRCA1 285 (52.0) 190 (48.2) 95 (61.7) .005
BRCA2 263 (48.0) 204 (51.8) 59 (38.3)
Relationship status
Married/partner 487 (88.9) 349 (88.6) 138 (89.6) .51
Single 54 (9.9) 41 (10.4) 13 (8.4)
Unknown 7 (1.3) 4 (1.0) 3 (1.9)
Offspring
No 62 (11.3) 46 (11.7) 16 (10.4) .72
Yes 476 (86.9) 343 (87.1) 133 (86.4)
Unknown 10 (1.8) 5 (1.3) 5 (3.2)
Educational level
Low 62 (11.3) 45 (11.4) 17 (11.0) .98
Medium 194 (35.4) 139 (35.3) 55 (35.7)
High 285 (52.0) 206 (52.3) 79 (51.3)
Unknown 7 (1.3) 4 (1.0) 3 (1.9)
Breast cancer in personal history
No 462 (84.3) 331 (84.0) 131 (85.1) .58
Yes 79 (14.4) 59 (15.0) 20 (13.0)
Unknown 7 (1.3) 4 (1.0) 3 (1.9)
Risk-reducing mastectomy
No 328 (59.9) 235 (59.6) 93 (60.4) .78
Yes 213 (38.9) 155 (39.3) 58 (37.7)
Unknown 7 (1.3) 4 (1.0) 3 (1.9)
First-degree family member with ovarian cancer
No 463 (84.5) 339 (86.0) 124 (80.5) .18
Yes 76 (13.9) 50 (12.7) 26 (16.9)
Unknown 9 (1.6) 5 (1.3) 4 (2.6)

Abbreviations: RRS, risk-reducing salpingectomy; RRSO, risk-reducing salpingo-oophorectomy.