Figure 2.
Native top-down ECD MS of anti-CD20 IgA1 and IgG1. (A) ECD spectra of intact anti-CD20 IgA1 (blue) and IgG1 (red) dominated by signals resulting from successive electron capture without dissociation. (B) Lower m/z spectral regions corresponding to the single-chain ECD fragments of intact anti-CD20 IgA1 (blue) and IgG1 (red).