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. 2021 May 3;104(6):2123–2130. doi: 10.4269/ajtmh.20-1209

Table 2.

Positive predictive value of malaria rapid diagnostic test by site, age, season, and presence of fever

Characteristic N (%)* Positive predictive value (95% CI)
All sites Chikhwawa Thyolo Ndirande
Total 7,202 (100.0) 77.8 (76.8–78.7) 77.1 (75.9–78.3) 78.2 (76.2–80.2) 80.5 (78.1–82.9)
Age group
 < 1 y 414 (5.8) 69.9 (65.5–74.2) 71.6 (66.5–76.8) 64.9 (54.0–75.7) 67.3 (54.9–79.7)
 1–5 y 2,334 (32.4) 75.6 (73.9–77.3) 74.7 (72.6–76.9) 77.0 (73.3–80.7) 77.9 (73.1–82.6)
 6–15 y 2,278 (31.6) 81.9 (80.3–83.4) 80.6 (78.6–82.7) 82.5 (79.2–85.8) 86.6 (82.8–90.4)
 > 15 y 2,176 (30.2) 77.4 (75.6–79.1) 77.0 (74.7–79.3) 77.0 (73.3–80.6) 79.3 (75.3–83.4)
 < 5 y 2,395 (33.3) 74.2 (72.5–76.0) 73.7 (71.5–75.8) 75.8 (72.0–79.7) 74.7 (69.7–79.6)
 ≥ 5 y 4,807 (66.7) 79.8 (78.7–81.0) 79.0 (77.6–80.5) 79.9 (77.5–82.4) 82.8 (80.1–85.5)
Season
 Rainy 4,194 (41.8) 78.9 (77.7–80.0) 78.9 (77.4–80.4) 79.6 (77.4–81.8) 77.2 (74.1–80.3)
 Dry 3,008 (58.2) 75.6 (73.9–77.3) 73.9 (71.9–76.0) 71.9 (66.8–77.0) 87.2 (83.7–90.7)
Any fever
 Presence 4,397 (61.2) 81.5 (80.1–83.0) 80.1 (78.2–81.9) 82.8 (79.7–86.0) 86.7 (83.2–90.2)
 Absence 2,791 (38.8) 75.1 (73.7–76.5) 75.5 (73.8–77.2) 74.8 (71.6–77.9) 73.8 (69.7–77.8)
*

Sample size for analysis.