Table 3.
Relationship of HDL-CEC and other HDL characteristics with cIMT, stratified for normoglycemia and (pre)diabetes
| HDL-characteristic (Z-Score) |
Model | cIMT (Z-Score) |
Pint | |||||
|---|---|---|---|---|---|---|---|---|
| NGM |
IGM&T2DM |
|||||||
| N = 268 |
N = 228 |
|||||||
| std β | 95% CI | P-value | std β | 95% CI | P-value | |||
| HDL-CEC | 1 | 0.062 | −0.056; 0.179 | .303 | −0.152 | −0.286; −0.017 | .028 | .019 |
| 2 | 0.059 | −0.052; 0.170 | .296 | −0.132 | −0.265; 0.001 | .051 | .023 | |
| 3 | 0.061 | −0.044; 0.167 | .255 | −0.129 | −0.263; 0.005 | .060 | .025 | |
| HDL-C | 1 | −0.057 | −0.172; 0.058 | .328 | −0.181 | −0.325; −0.038 | .014 | .184 |
| 2 | −0.035 | −0.150; 0.079 | .545 | −0.138 | −0.287; 0.012 | .071 | .216 | |
| 3 | −0.044 | −0.158; 0.070 | .446 | −0.138 | −0.293; 0.017 | .081 | .169 | |
| ApoA-I | 1 | 0.007 | −0.111; 0.125 | .905 | −0.188 | −0.325; −0.025 | .007 | .033 |
| 2 | 0.031 | −0.088; 0.149 | .611 | −0.132 | −0.277; 0.014 | .076 | .075 | |
| 3 | 0.011 | −0.105; 0.128 | .848 | −0.118 | −0.268; 0.031 | .120 | .067 | |
| HDL size | 1 | −0.088 | −0.196; 0.021 | .114 | −0.056 | −0.207; 0.095 | .465 | .737 |
| 2 | −0.061 | −0.172; 0.050 | .279 | −0.009 | −0.165; 0.147 | .908 | .823 | |
| 3 | −0.055 | −0.167; 0.056 | .329 | −0.006 | −0.170; 0.159 | .947 | .910 | |
| HDL-P | 1 | −0.007 | −0.130; 0.115 | .909 | −0.169 | −0.298; −0.039 | .011 | .061 |
| 2 | 0.043 | −0.081; 0.167 | .496 | −0.112 | −0.253; 0.029 | .118 | .080 | |
| 3 | 0.006 | − 0.115; 0.128 | .919 | −0.132 | −0.276; 0.012 | .073 | .038 | |
Std β, standardized regression coefficient.
Linear regression analyses, Model 1: crude, Model 2: adjusted for age, sex, Model 3 additionally adjusted for smoking, BMI, medication usage (antihypertensive, glucose- and lipid-lowering), physical activity, caloric intake, systolic and diastolic blood pressure, fasting plasma glucose, and glucose metabolism state.