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. 2021 Jun 4;22(Suppl 3):405. doi: 10.1186/s12864-021-07717-9

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 5 — The enriched sequence motifs in the 60 LTRs activated at the early stages of reprogramming rhesus monkey fibroblast cells to NESCs. (A) The five motifs with the smallest E-values and their corresponding putative TFs. (B) The expression levels of the TFs in Part (A). Only those TFs with at least 5 FPKM in at least one of the 7 samples and standard deviation values of at least 5 FPKM were shown. (C) The distribution of motifs on some of the selected LTRs. M1 to M5 represents Motif 1 to Motif 5 in Part (A), respectively. (D) The bidirectional clustering of TEs and TFs in Part (B) based on the correlation coefficient values of their expression levels