Table 2.
Classification of the 211 HCC patients who underwent hepatectomy in the training cohort
| Variables | Single segment-HCC (n = 151) | Multiple segments-HCC (n = 60) | Single segment vs. Multiple segments (P-value) |
|||
|---|---|---|---|---|---|---|
| Left segment (n = 64) |
Middle segment (n = 28) | Right segment (n = 58) | Caudate area (n = 1) | |||
| Tumor size (cm) | 6.5 ± 4.8 | 4.0 ± 2.8 | 4.8 ± 2.5 | 8.5 | 7.1 ± 3.3 | 0.002 |
| Tumor nodule number | < 0.001 | |||||
| Single | 58 (90.6%) | 24 (85.7%) | 51 (87.9%) | 1 (100%) | 37 (61.7%) | |
| Multiple (≥ 2) | 6 (9.4%) | 4 (14.3%) | 7 (12.1%) | 0 | 23 (38.3%) | |
| Capsulation formation | 0.540 | |||||
| Present | 39 (60.9%) | 15 (53.6%) | 34 (58.6%) | 0 | 32 (53.3%) | |
| Absent | 25 (39.1%) | 13 (46.4%) | 24 (41.4%) | 1 (100%) | 28 (46.7%) | |
| Differentiation gradea | 0.801 | |||||
| I–II | 61 (95.3%) | 25 (89.3%) | 49 (84.5%) | 1 (100%) | 55 (91.7%) | |
| III–IV | 3 (4.7%) | 3 (10.7%) | 9 (15.5%) | 0 | 5 (8.3%) | |
| MVI | 1.000 | |||||
| Present | 18 (28.1%) | 5 (17.9%) | 16 (27.6%) | 0 | 16 (26.7%) | |
| Absent | 46 (71.9%) | 23 (82.1%) | 42 (72.4%) | 1 (100%) | 44 (73.3%) | |
| Liver cirrhosis | 0.715 | |||||
| Present | 53 (82.8%) | 18 (64.3%) | 44 (73.3%) | 0 | 50 (83.3%) | |
| Absent | 11 (17.2%) | 10 (35.7%) | 14 (26.7%) | 1 (100%) | 10 (16.7%) | |
| BCLC stage | 0.161 | |||||
| 0 & A | 34 (53.1%) | 20 (71.4%) | 44 (73.3%) | 1 (100%) | 27 (45.0%) | |
| B | 3 (4.7%) | 4 (14.3%) | 0 | 0 | 16 (26.7%) | |
| C | 27 (42.2%) | 4 (14.3%) | 14 (26.7%) | 0 | 17 (28.3%) | |
BCLC Barcelona Clinic Liver Cancer, MVI microvascular invasion, HCC hepatocellular carcinoma
aEdmondson–Steiner grade