Table 1.
Characteristics of the patient cohort with troponin and neurofilament light data. ASA, American Society of Anesthesiologists; AUC BP <10%, area under curve for blood pressure <90% of baseline; NSQIP-D, National Surgical Quality Improvement Program Risk of Death; TIA, transient ischaemic attack; TPN, postoperative troponin negative patient; TPP, postoperative troponin positive patient.
| Perioperative myocardial injury (PMI n=94) |
Postoperative troponin analysis (n=94) |
|||
|---|---|---|---|---|
| PMI+patients (n=23) | PMI–patients (n=71) | TPP (n=34) | TPN (n=60) | |
| Age (yr) | 68.4 (10.0) | 71.1 (5.1) | 69.5 (8.6) | 70.9 (5.3) |
| Female sex | 10 (43%) | 30 (42%) | 14 (41%) | 26 (43%) |
| ASA physical status >2 | 16 (70%) | 41 (63%) | 21 (62%) | 38 (63%) |
| NSQIP-D | 4.8 (7.0) | 2.1 (3.3) | 3.8 (6.0) | 2.1 (3.4) |
| Smoker | 8 (35%) | 12 (17%) | 9 (26%) | 11 (18%) |
| Chronic obstructive pulmonary disease | 5 (22%) | 7 (10%) | 6 (18%) | 6 (10%) |
| Obstructive sleep apnoea | 2 (9%) | 22 (31%) | 4 (12%) | 20 (33%) |
| BMI (kg m−2) | 29.0 (6.6) | 29.0 (5.9) | 28.9 (5.6) | 28.9 (6.2) |
| BP (systolic; mm Hg) | 134 (17) | 134 (19) | 133 (15) | 134 (19) |
| Hypertension | 18 (78%) | 48 (68%) | 27 (79%) | 39 (65%) |
| Stroke/TIA | 3 (13%) | 3 (4%) | 3 (9%) | 3 (5%) |
| Vascular surgery | 18 (78%) | 26 (37%) | 20 (59%) | 24 (40%) |
| Blood loss (ml) | 3783 (43 780) | 1176 (1866) | 2856 (3884) | 1223 (1967) |
| Operation time (min) | 458 (187) | 297 (131.8) | 384 (196) | 309 (134) |
| Intraoperative hypotension (AUC BP <90%) | 241 967 (205 820) | 127 384 (148 067) | 172 744 (187 251) | 140 298 (156 641) |
| Renal failure | 1 (4%) | 2 (3%) | 2 (6%) | 1 (2%) |
| Coronary artery disease | 3 (13%) | 9 (13%) | 4 (12%) | 8 (13%) |