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. 2021 Jun 1:10.2217/fvl-2020-0394. doi: 10.2217/fvl-2020-0394

Figure 1. Illustration of five druggable cavity pockets within the monomeric SARS-CoV-2 spike glycoprotein.

Figure 1.

Pocket No.10 (shown in red) was the largest cavity and selected for pharmacophore modeling. Receptor-binding domain (residues 331–438) is represented in pink. In addition, heptad repeats 1 (HR1) and 2 (HR2) are depicted in light green and black, respectively.