Fig. 1.

Hypoxia treatment elevated circ_0001982 expression in a time-dependent manner. a The expression of circ_0001982 in BC tissues (n = 35) and adjacent normal tissues (n = 35) was measured by qRT-PCR analysis. b The level of circ_0001982 in BC cells (MDA-MB-231 and MDA-MB-468) and breast epithelial cells (MCF-10A) was determined by qRT-PCR analysis. c, d QRT-PCR assay was conducted to evaluate the abundance of circ_0001982 in BC cells (MDA-MB-231 and MDA-MB-468) under hypoxia at time points (0 h, 3 h, 6 h, 12 h, 24 h, 48 h). e, f The cellular localization of circ_0001982 in MDA-MB-231 and MDA-MB-468 cells was analyzed by subcellular fractionation. *P < 0.05