Fig. 7.

Identification of common genes related to plaques in the ImmuneScoreL and ImmuneScoreH clusters. CAPG: actin regulatory protein CAP-G, IGSF6: immunoglobulin superfamily member 6, IL18: interleukin-18, CECR1: cat eye syndrome critical region protein 1, FBP1: fructose-bisphosphatase 1, MMP7: matrix metallopeptidase 7. A Pearson correlation coefficients obtained for the correlations of CAPG, CECR1, IL18, IGSF6, and FBP1 with the relative proportions of M0 macrophages, gamma delta T cells, plasma cells and monocytes in the ImmuneScoreL cluster. B Scatterplot showing the correlations of the relative expression levels of CAPG, CECR1, IL18, IGSF6, and FBP1 to the relative proportions of M0 macrophages, gamma delta T cells, plasma cells and monocytes in the ImmuneScoreL cluster. C Pearson correlation coefficients obtained for the correlations of CAPG and MMP7 with the relative proportion of M0 macrophages, gamma delta T cells, plasma cells and monocytes in the ImmuneScoreH cluster. D Scatterplot showing the correlations of the relative expression levels of CAPG and MMP7 to the relative proportions of M0 macrophages, gamma delta T cells, plasma cells and monocytes in the ImmuneScoreH cluster. E Pearson correlation coefficients obtained for the correlations of CAPG with the relative proportion of M0 macrophages, gamma delta T cells, plasma cells and monocytes in the healthy controls. F Scatterplot showing the correlations of the relative expression levels of CAPG to the relative proportions of M0 macrophages, gamma delta T cells, plasma cells and monocytes in the healthy controls. The grey-shaded areas in the scatterplots represent the standard errors of the regression lines. R: correlation coefficient. The p values of all these genes were < 0.05 except for the correlation of the relative expression levels of CAPG to the relative proportions of gamma delta T cells in F