Table 3.
Statistical analysis for electrophysiological characteristicsa
| Kruskal–Wallisb | Pairwise comparisonsc |
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|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Kcng4+ vs Npas1+ | Kcng4+ vs Npas1+-Lhx6+ | Kcng4+ vs Npr3+ | Kcng4+ vs Npy2r+ | Kcng4+ vs PV+ | Kcng4+ vs PV+-Lhx6+ | Kcng4+ vs PV+-Npy2r+ | Npas1+ vs Npas1+-Lhx6+ | Npas1+ vs Npr3+ | Npas1+ vs Npy2r+ | Npas1+ vs PV+ | Npas1+ vs PV+-Lhx6+ | Npas1+ vs PV+-Npy2r+ | Npas1+-Lhx6+ vs Npr3+ | ||
| Spontaneous activity (Hz) | <0.0001 | 0.0019 | 0.0037 | 0.014 | 0.38 | >0.99 | >0.99 | >0.99 | >0.99 | >0.99 | >0.99 | <0.0001 | 0.057 | 0.00010 | >0.99 |
| CVISI | <0.0001 | 0.014 | 0.97 | >0.99 | >0.99 | >0.99 | >0.99 | >0.99 | >0.99 | >0.99 | >0.99 | <0.0001 | 0.011 | <0.0001 | >0.99 |
| Max rate (Hz) | <0.0001 | <0.0001 | 0.0014 | 0.0040 | >0.99 | >0.99 | >0.99 | >0.99 | >0.99 | >0.99 | 0.0029 | <0.0001 | 0.0059 | <0.0001 | >0.99 |
| Max current (pA) | <0.0001 | <0.0001 | 0.046 | 0.019 | >0.99 | >0.99 | >0.99 | >0.99 | >0.99 | >0.99 | <0.0001 | <0.0001 | 0.022 | <0.0001 | >0.99 |
| Membrane potential (mV) | 0.26 | >0.99 | >0.99 | >0.99 | >0.99 | >0.99 | >0.99 | >0.99 | >0.99 | >0.99 | >0.99 | >0.99 | 0.38 | 0.79 | >0.99 |
| Trough potential (mV) | <0.0001 | <0.0001 | <0.0001 | 0.0021 | >0.99 | >0.99 | 0.38 | >0.99 | >0.99 | >0.99 | <0.0001 | <0.0001 | 0.072 | <0.0001 | >0.99 |
| Sag ratio | 0.00011 | 0.00013 | >0.99 | >0.99 | >0.99 | >0.99 | >0.99 | 0.99 | 0.022 | >0.99 | 0.10 | <0.0001 | 0.19 | 0.099 | >0.99 |
| First/last ISI ratio | <0.0001 | <0.0001 | 0.028 | 0.010 | >0.99 | 0.019 | >0.99 | >0.99 | 0.40 | >0.99 | 0.00036 | 0.0014 | 0.00031 | <0.0001 | >0.99 |
| Spike height (mV) | 0.036 | >0.99 | >0.99 | >0.99 | >0.99 | >0.99 | >0.99 | >0.99 | >0.99 | >0.99 | >0.99 | >0.99 | >0.99 | >0.99 | >0.99 |
| Spike width (ms) | <0.0001 | <0.0001 | <0.0001 | 0.0016 | >0.99 | >0.99 | >0.99 | >0.99 | >0.99 | >0.99 | 0.0086 | <0.0001 | 0.0041 | <0.0001 | >0.99 |
| Pairwise comparisonsc |
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| Npas1+-Lhx6+ vs Npy2r+ | Npas1+-Lhx6+ vs PV+ | Npas1+-Lhx6+ vs PV+-Lhx6+ | Npas1+-Lhx6+ vs PV+-Npy2r+ | Npr3+ vs Npy2r+ | Npr3+ vs PV+ | Npr3+ vs PV+-Lhx6+ | Npr3+ vs PV+-Npy2r+ | Npy2r+ vs PV+ | Npy2r+ vs PV+-Lhx6+ | Npy2r+ vs PV+-Npy2r+ | PV+ vs PV+-Lhx6+ | PV+ vs PV+-Npy2r+ | PV+-Lhx6+ vs PV+-Npy2r+ | ||
| Spontaneous activity (Hz) | >0.99 | <0.0001 | 0.081 | 0.00050 | >0.99 | <0.0001 | 0.16 | 0.0050 | 0.029 | >0.99 | 0.26 | >0.99 | >0.99 | >0.99 | |
| CVISI | >0.99 | 0.0043 | >0.99 | 0.020 | >0.99 | 0.98 | >0.99 | 0.68 | >0.99 | >0.99 | >0.99 | >0.99 | >0.99 | >0.99 | |
| Max rate (Hz) | 0.053 | <0.0001 | 0.11 | <0.0001 | 0.067 | <0.0001 | 0.13 | 0.00059 | >0.99 | >0.99 | >0.99 | >0.99 | >0.99 | >0.99 | |
| Max current (pA) | 0.095 | 0.0018 | >0.99 | 0.050 | 0.038 | 0.0011 | >0.99 | 0.022 | >0.99 | >0.99 | >0.99 | 0.30 | >0.99 | >0.99 | |
| Membrane potential (mV) | >0.99 | >0.99 | >0.99 | >0.99 | >0.99 | >0.99 | >0.99 | >0.99 | >0.99 | >0.99 | >0.99 | >0.99 | >0.99 | >0.99 | |
| Trough potential (mV) | <0.0001 | <0.0001 | >0.99 | 0.00026 | 0.0015 | 0.0067 | >0.99 | 0.016 | >0.99 | 0.21 | >0.99 | >0.99 | >0.99 | >0.99 | |
| Sag ratio | >0.99 | >0.99 | >0.99 | >0.99 | >0.99 | >0.99 | >0.99 | >0.99 | >0.99 | >0.99 | >0.99 | >0.99 | >0.99 | >0.99 | |
| First/last ISI ratio | >0.99 | >0.99 | >0.99 | 0.28 | 0.64 | >0.99 | 0.79 | 0.090 | >0.99 | >0.99 | >0.99 | >0.99 | 0.28 | >0.99 | |
| Spike height (mV) | 0.47 | >0.99 | >0.99 | >0.99 | 0.33 | 0.75 | >0.99 | >0.99 | >0.99 | 0.30 | >0.99 | 0.61 | >0.99 | >0.99 | |
| Spike width (ms) | 0.0043 | <0.0001 | 0.0023 | <0.0001 | 0.27 | 0.0091 | 0.21 | 0.00038 | >0.99 | >0.99 | >0.99 | >0.99 | >0.99 | >0.99 | |
aTwo-tailed p values are listed.
bKruskal–Wallis tests were performed to compare each characteristic across all groups.
cDunn tests were performed to compare each pair of neuron types.
The bolded p values are significant when using a Bonferroni correction at a significance level of 0.05, adjusting for the fact that 10 characteristics were considered.