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. 2021 May 26;13(5):386–415. doi: 10.4252/wjsc.v13.i5.386

Figure 4.

Figure 4

Overview of key strategies to enhance stem cell transplantation therapy. The steps of stem cell-based transplantation therapy include drawing the materials, isolation, culture, proliferation, and transplantation. Compared with the classic approaches, pre-strategies could enhance survival of stem cells. These pre-strategies mainly include preconditioning, pretreatment, genetic strategies, and other methods. They can effectively activate various signaling pathways for protecting cells from injury and promoting survival.