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. 2021 May 21;12:670971. doi: 10.3389/fimmu.2021.670971

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Copyright © 2021 Deng, Yin, Zhang, Zhou and Hou

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Weighted co-expression network analysis. (A) Sample dendrogram and trait heat map; (B) Analysis of the scale-free fit index (left) and the mean connectivity (right) for various soft-thresholding powers; (C) Clustering dendrograms of genes based on a dissimilarity measure (1-TOM); (D) Module-trait associations were evaluated by correlations between module eigengenes and sample traits. (E–G) Scatterplot of Gene Significance for COPD, FEV1/FVC, FEV1% predicted vs. Module Membership in brown module.