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(a) Overview of TNS1 variant locations for patient #160 (b) TNS1 rs918949 C>T, (c) TNS1 rs2571445 A>G, (d) TNS1 rs3796028 G>A (e) Cartoon structure of TNS1. TNS1 918949 is located on the phosphotyrosine binding domain (PTB) which binds to the β1 tail of the fibronectin‐binding integrin, α5β1 integrin. TNS1 rs2571445 and TNS1 rs3796028 are located on the actin binding domain II (ABDII) region, which controls the polymerization of cytosolic actin
