Table 4. Univariate and multivariate Cox regression analyses of OS for CRC patients in the Zhongshan cohort.

Variables	Univariate analysis			Multivariate analysis
	HR	95% CI	P value	HR	95% CI	P value
age	1.113	[0.597–2.073]	0.736
sex	1.282	[0.696–2.366]	0.427
grade	2.241	[1.141–4.4]	0.455
T stage	1.503	[0.665–3.397]	0.327
N stage	1.751	[0.948–3.233]	0.07
M stage	12.519	[5.880-26.652]	<0.001			0.240
TNM stage	4.497	[2.784–7.265]	<0.001	3.850	[2.375–6.241]	<0.001
Tumor size	0.614	[0.238–1.152]	0.129
PHF19	7.401	[2.274–24.09]	0.001	4.031	[1.202–13.516]	0.025
Liver metastasis	11.826	[5.687–24.594]	<0.001			0.117
CA19-9	0.417	[0.214–0.811]	0.01			0.261