Table 1.
Failures and salvage interventions, with current status
| Failure | Stage/site | Group assignment | Site of failure | Time to failure, mo | Treatment | Status (mo) |
|---|---|---|---|---|---|---|
| 1 | T1N2aM0/right tonsil | Group 1 (observational) | Ipsilateral neck |
11.5 – neck 22.0 – lung metastasis |
Salvage ND + CCRT, RT for lung metastasis | AWD (16) |
| 2 | T1N2aM0/left tonsil | Group 1 (observational) | Local | 3.8 | Salvage CCRT | NED (21) |
| 3 | T2N2bM0/left tonsil | Group 2 (radiation) | Contralateral neck | 9.7 | Salvage ND + CCRT | NED (41) |
| 4 | T1N2aM0/Left tonsil | Group 2 (radiation) | Contralateral right tonsil (second primary) | 59.0 | Salvage TORS + XRT | NED (11) |
| 5 | T2N2aM0/right tonsil | Group 3 (chemoradiation) | Local | 9.8 | Salvage resection, CCRT proton | NED (42) |
Abbreviations: AWD, alive with disease; CCRT, concurrent chemoradiotherapy; ND, neck dissection; NED, no evidence of disease; RT, radiotherapy; TORS, transoral robotic surgery; XRT, radiotherapy for consistency.