Table 2 –

Studies reporting the outcomes of patients after aborted radical cystectomy for intraoperative findings of grossly enlarged lymph nodes and locally advanced tumor

Reference	No. of cases	Findings	PLND at time of aborted RC	Chemotherapy after aborted RC	Median follow-up (mo)	Survival	Comment
Guzzo et al [21]	35	Grossly enlarged LNs: 91% pT4:23%	31	30	18.5	60% died from the disease 31% alive with evidence of disease persistence or re-progression. 9% alive with no evidence of disease	Subsequent salvage RC: 23%. 43% had no evidence of disease progression at a mean time of 10 mo after salvage RC
Yafi et al [22]	31	Clinical T≥2: 45% Clinical N1: 10% Pathological T4b: 55 Pathological N2–3: 45%	20	23	10	2-yr OS: 41% 5-yr OS: 0% Patients who underwent RPLND trended toward improved OS (24 vs 10 mo, p = 0.09)	35% received CHT with intention to surgical consolidation, only 9% rendered resectable

CHT = chemotherapy; LN = lymph node; OS = overall survival; PLND = pelvic lymph node dissection; RC = radical cystectomy.