Skip to main content
. Author manuscript; available in PMC: 2021 Aug 1.
Published in final edited form as: Biochim Biophys Acta Mol Basis Dis. 2021 Apr 22;1867(8):166153. doi: 10.1016/j.bbadis.2021.166153

Fig. 6.

Fig. 6.

Regulation of FXR target genes in vivo after treatment with unconjugated and conjugated bile acids. C57BL/6 J mice were treated with cholic (CA) and taurocholic (TCA), ursodeoxycholic (UDCA) and tauroursodeoxycholic (TUDCA) acid 0.5% (w/w) chow diet. (A-B) Regulation of intestinal Fgf15 and Ibabp pre-mRNA and mRNA by CA, TCA, UDCA, and TUDCA. (C–D) Repression of hepatic bile acids synthesis genes (Cyp7a1 and Cyp8b1) by CA, TCA, UDCA, and TUDCA. n = 4–5, values represent the mean ± SEM. *p < 0.05; #p < 0.01.