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. 2021 Apr 27;12(2):162–168. doi: 10.4103/japtr.JAPTR_254_20

Table 1.

Antibacterial activities of different Carissa carandas fruit extracts

Carissa carandas fruit extracts Cutibacterium acnes Staphylococcus epidermidis Staphylococcus aureus



IZ (mm) MIC (mg/mL) MBC (mg/mL) IZ (mm) MIC (mg/mL) MBC (mg/mL) IZ (mm) MIC (mg/mL) MBC (mg/mL)
Fresh unripe 9.00±1.00 6.25 12.5 7.33±0.58 12.5 50.0 ND - -
Fresh ripe 7.67±0.58 6.25 12.5 7.00±0.00 12.5 50.0 ND - -
Fresh fully ripe 7.00±0.00 6.25 12.5 7.00±0.00 12.5 50.0 ND - -
Dried unripe 12.33±1.15 6.25 12.5 7.67±0.58 12.5 50.0 8.00±1.00 12.5 25.0
Dried ripe 11.33±1.53 6.25 6.25 7.33±0.58 12.5 25.0 7.33±0.58 12.5 25.0
Dried fully ripe 6.67±0.58 6.25 6.25 7.00±0.00 12.5 100.0 6.67±0.58 12.5 25.0
Ampicillin 10 ug/ml - - - 9.00±1.00 0.0625 >0.5 21.00±1.00 0.03125 >0.25
Clindamycin 2 ug/ml 26.33±0.58 0.0125 0.05 - - - - - -

IZ: Inhibition zone, MIC: Minimum inhibitory concentration, MBC: Minimal bactericidal concentration, ND: Not detected; -: Not tested