Table 3.

Binding affinity of anti-Severe acute respiratory syndrome-coronavirus-2 spike glycoprotein candidates

C_ID	Compounds	Plant	Binding affinity (kcal/mol)
C00003672	(−)-beta-sitosterol	Z. officinale, T. capitatus[8,9]	−8.4
C00029372	10-Methoxycamptothecin	C. acuminata[6]	−8.2
C00035841	Inoxanthone	C. inophyllum[7]	−8.1
C00001849	Emetine	C. ipecacuanha[10]	−7.7
C00003111	Alpha-cedrene	Z. officinale[11]	−7.6
C00032554	Zonarene	Z. officinale[12]	−7.6
C00000720	Justicidin D	J. procumbens[4]	−7.6
C00032769	Bis-demethoxycurcumin	C. longa[13]	−7.5
C00020351	Curcumenol	C. longa[14]	−7.5
C00012483	Beta-caryophyllene epoxide	C. zanthorrhiza[15]	−7.5
C00001566	Caribine	H. arenicola[16]	−7.5

Z. officinale: Zingiber officinale, T. capitatus: Thymus capitatus, C. acuminata: Camptotheca acuminata, C. inophyllum: Calophyllum inophyllum, J. procumbens: Justicia procumbens, C. longa: Curcuma longa, C. zanthorrhiza: Curcuma zanthorrhiza, H. arenicola: Hymenocallis arenicola, C. ipecacuanha: Carapichea ipecacuanha