Table 4.

Binding affinity of anti-severe acute respiratory syndrome-coronavirus-2 3C-like protease candidates

C_ID	Compounds	Plant	Binding affinity (kcal mol−1)
C00001566	Caribine	H. arenicola[16]	−9.0
C00002331	Cryptopleurine	T. indica[17]	−8.2
C00000720	Justicidin D	J. procumbens[7]	−8.1
C00002600	Diphyllin	J. gendarussa[18]	−8.0
C00004632	Quercetin 3-O-methyl ether	Widespread in medicinal plants	−7.9
C00004631	Quercetin	Widespread in medicinal plants	−7.9
C00000677	Dihydroquercetin	Widespread in medicinal plants	−7.9
C00001576	Lycorine	L. radiata[19]	−7.9
C00000674	Luteolin	Widespread in medicinal plants	−7.9
C00013411	Moralbanone	Morus alba L.[20]	−7.8
C00000963	(2R,3R)-fustin	R. verniciflua[21]	−7.8

H. arenicola: Hymenocallis arenicola, T. indica: Tylophora indica, Justicia procumbens: J. procumbens, J. gendarussa: Justicia gendarussa, L. radiata: Lycoris radiata, R. verniciflua: Rhus verniciflua