Table 2.
Laboratory indices of COVID-19 patients at admission who did or did not develop ARDS
| Index | ARDS (n = 64) | Non-ARDS (n = 30) | P value |
|---|---|---|---|
| Blood counts | |||
| White blood cells, × 109/L | 9.73 ± 5.42 | 5.31 ± 1.97 | < 0.001 |
| Neutrophils, × 109/L | 8.456 ± 5.15 | 3.99 ± 1.80 | < 0.001 |
| Monocytes, × 109/L | 0.52 ± 0.42 | 0.39 ± 0.21 | 0.070 |
| Lymphocytes, × 109/L | 0.76 ± 0.58 | 1.05 ± 0.43 | 0.016 |
| Platelets, × 109/L | 201.41 ± 120.11 | 205.4 ± 82.80 | 0.852 |
| Lymphopenia, n (%) | 55 (85.9%) | 19 (63.3%) | 0.013 |
| Thrombocytopenia, n (%) | 20 (31.3%) | 4 (13.3%) | 0.063 |
| Hemoglobin, g/L | 124.13 ± 22.18 | 127.80 ± 19.15 | 0.437 |
| Serum biochemistry | |||
| ALT, U/L | 36.59 ± 33.15 | 28.47 ± 23.30 | 0.117 |
| AST, U/L | 46.28 ± 25.78 | 35.17 ± 29.80 | 0.067 |
| TBIL, µmol/L | 15.73 ± 10.58 | 9.35 ± 4.13 | 0.041 |
| LDH, U/L | 511.19 ± 264.81 | 276.30 ± 127.25 | < 0.001 |
| Creatinine, µmol/L | 105.40 ± 126.52 | 78.57 ± 36.10 | 0.258 |
| Urea nitrogen, mmol/L | 9.73 ± 7.23 | 4.96 ± 2.47 | 0.001 |
| Albumin, g/L | 31.68 ± 6.10 | 34.34 ± 3.18 | 0.027 |
| Inflammatory markers | |||
| ESR, mm/h | 44.37 ± 26.92 | 35.93 ± 23.00 | 0.197 |
| hsCRP, mg/L | 105.96 ± 69.63 | 47.30 ± 40.59 | < 0.001 |
| PCT, ng/mL | 0.85 ± 1.36 | 0.07 ± 0.05 | < 0.001 |
| Coagulation markers | |||
| D-dimer, µg/mL | 7.59 ± 8.07 | 1.42 ± 2.05 | < 0.001 |
| PT, s | 16.39 ± 4.89 | 13.97 ± 0.85 | < 0.001 |
| APTT, s | 45.86 ± 12.47 | 43.30 ± 8.13 | 0.309 |
| Fib, g/L | 5.42 ± 1.97 | 5.17 ± 0.89 | 0.401 |
Data are presented as mean ± SD or n (%)
ALT alanine aminotransferase, AST aspartate aminotransferase, TBIL total bilirubin, LDH lactate dehydrogenase, ESR erythrocyte sedimentation rate, hsCRP high-sensitivity C-reactive protein, PCT procalcitonin, PT prothrombin time, APTT activated partial prothrombin time, Fib fibrinogen