Table 5.

Levels of inflammatory cytokines at admission in different subgroups of patients who developed ARDS (n = 42)*

Outcome	Subgroups	IL-6	P value	IL-8	P value	IL-10	P value	TNF-α	P value
Septic shock	Yes (n = 33)	54.88 (26.64–161.65)	0.29	21.90 (13.05–60.70)	0.417	10.50 (5.30–20.05)	0.127	10.3 (7.15–19.70)	0.391
	No (n = 9)	31.76 (19.30–72.91)		29.9 (20.20–72.10)		6.10 (4.25–13.35)		9.3 (7.6–10.7)
DIC	Yes (n = 21)	96.99 (37.62–214.90)	< 0.001	47.00 (19.3–103.25)	0.016	14.40 (5.85–25.4)	0.006	11.0 (7.8–26.4)	0.131
	No (n = 21)	29.32 (11.23–47.98)		17.50 (11.95–30.45)		6.20 (5.0–9.85)		9.30 (7.15–12.35)
AKI	Yes (n = 21)	59.83 (31.02–200.90)	0.013	30.50 (15.55–103.25)	0.199	10.70 (5.40–20.05)	0.087	11.30 (8.4–26.4)	0.047
	No (n = 21)	35.50 (18.11–106.09)		22.90 (12.75–55.20)		6.4 (5.0–13.20)		9.30 (6.85–10.9)
Cardiac injury	Yes (n = 33)	59.83 (26.64–161.65)	0.112	30.30 (14.50–75.25)	0.567	10.7 (5.3–20.05)	0.112	10.30 (7.30–19.70)	0.171
	No (n = 9)	29.54 (19.30–47.98)		22.90 (15.45–48.55)		6.1 (4.23–11.0)		9.30 (6.9–9.77)
Hepatic injuryy	Yes (n = 13)	64.78 (34.74–186.15)	0.268	30.30 (16.80–89.60)	0.419	10.08 (5.3–25.4)	0.332	11.30 (7.45–41.55)	0.257
	No (n = 29)	43.38 (20.98–99.99)		21.90 (13.70–68.45)		7.9 (5.12–15.0)		9.5 (7.5–13.05)
28-day survival	No (n = 32)	60.46 (30.36–185.03)	0.018	30.01 (14.25–71.93)	0.432	10.8 (5.4–24.08)	0.014	10.30 (7.48–19.68)	0.247
	Yes (n = 10)	28.81 (10.12–47.55)		23.95 (16.48–42.50)		5.5 (4.19–8.18)		8.6 (6.45–10.50)

^*After exclusion of 22 patients, as indicated in Fig. 1

DIC disseminated intravascular coagulation, AKI acute kidney injury