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. 2021 Jun 4;16(6):e0252649. doi: 10.1371/journal.pone.0252649

Fig 1. Echocardiographic evaluation of PKP2 mice during 16 weeks of physical activity.

Fig 1

Exemplary echocardiographic original traces from mice recorded pre run/sed (A), after 8 weeks of running (B) and after 16 weeks of running (C). There was no difference between the genotypes at baseline in the functional characteristics ejection fraction (EF) and fractional shortening (FS) (D). Heterozygous PKP2 mice (he) showed a reduction in EF after 8 weeks of running, which was normalized after 16 weeks (E). Heterozygous animals also showed a reduction in FS after 8 weeks of running which normalized again at 16 weeks (F).