Table 3. Cox proportional regression analysis of the correlation of clinical factors and the lncRNA signature risk score with OS in BCa patients.
Variables | Univariate analysis | P value | Multivariate analysis | P value |
---|---|---|---|---|
HR (95%CI) | HR (95%CI) | |||
Menopause (Indeterminate VS Peri VS Post VS Pre) | 1.036 (0.749,1.431) | 0.832 | 0.668 (0.438,1.018) | 0.061 |
Tumor Status (Tumor free VS With tumor) | 11.869(6.384,22.065) | <0.001 | 13.974(6.753,28.915) | <0.001 |
Age (<65 VS. ≥65) | 1.032 (1.009,1.057) | 0.007 | 1.065 (1.035,1.095) | <0.001 |
Surgical (Lumpectomy VS Modified Radical Mastectomy VS Other VS Simple Mastectomy) | 1.091 (0.829,1.437) | 0.533 | 1.150 (0.852,1.553) | 0.362 |
T (T1 vs T2 VS T3 VS T4) | 1.365 (0.950,1.961) | 0.092 | 0.814 (0.492,1.347) | 0.423 |
N (N0 vs N1 VS N2 VS N3 VS Nx) | 2.053 (1.640,2.737) | <0.001 | 1.390 (0.846,2.283) | 0.194 |
M (M0 VS M1 VS Mx) | 3.504 (1.365,8.992) | 0.009 | 0.305 (0.074,1.249) | 0.099 |
Stage (I VS. II VS. III VS IV) | 2.297 (1.586,3.327) | <0.001 | 1.223 (0.518,2.889) | 0.646 |
RiskScore (high VS. low) | 1.069 (1.041,1.098) | <0.001 | 1.077 (1.047,1.109) | <0.001 |
HR: hazard ratio; CI: confidence interval.