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. 2021 Jun 4;16(6):e0252817. doi: 10.1371/journal.pone.0252817

Table 4. Effects of vaping on birth outcomes and breastfeeding.

Outcome Not vaping (N = 4,322) Vaping (N = 99) Unadjusted Adjusted for smoking pattern only Adjusted for sociodemographic characteristics only3 Adjusted for smoking pattern and sociodemographic characteristics4
Mean (SE)2 Mean (SE)2 Difference (95% CI)2 p-value Difference (95% CI)2 p-value Difference (95% CI)2 p-value Difference (95% CI)2 p-value
Birthweight5, grams 3,365 (9.19) 3,387 (55.21) -39.7 (-130.3 to 51.0) 0.391 -29.8 (-124.6 to 64.9) 0.537 -41.7 (-132.6 to 49.2) 0.368 -31.7 (-125.8 to 62.5) 0.509
Gestational age, weeks 39.2 (0.03) 39.0 (0.23) -0.21 (-0.58 to 0.17) 0.287 -0.18 (-0.57 to 0.22) 0.378 -0.19 (-0.57 to 0.19) 0.326 -0.18 (-0.58 to 0.21) 0.357
n1 (%2) n1 (%2) Risk ratio (95% CI)2 p-value Risk ratio (95% CI)2 p-value Risk ratio (95% CI)2 p-value Risk ratio (95% CI)2 p-value
Preterm birth 303 (7.34) 8 (9.37) 1.28 (0.57 to 1.98) 0.394 1.30 (0.54 to 2.05) 0.390 1.25 (0.55 to 1.95) 0.444 1.29 (0.54 to 2.04) 0.403
Initiation of breastfeeding 3,847 (85.60) 79 (75.12) 0.88 (0.79 to 0.97) 0.001 1.03 (0.97 to 1.08) 0.379 1.00 (0.95 to 1.06) 0.973 1.03 (0.98 to 1.08) 0.210
Breastfeeding for at least 8 weeks 2,848 (61.48) 42 (41.36) 0.67 (0.53 to 0.81) <0.001 0.99 (0.84 to 1.14) 0.914 0.92 (0.79 to 1.05) 0.201 1.04 (0.91 to 1.17) 0.571

1Unweighted

2Weighted

3Adjusting for age of woman, country of birth, education and IMD quintile

4Adjusting for smoking pattern in pregnancy, in addition to age of woman, country of birth, education and IMD quintile

5Gestational age-adjusted