Fig 6. Intracellular expression of HSPGs, HS and HPSE in wt and db/db isolated islet cells.

Intracellular levels of (A, D) HSPG core proteins COL18, SDC1 and CD44, (B, E) HS and (C, F) HPSE in wt (open bars) and db/db (shaded bars) isolated islet cells on day 0 and after culture for 2 days (day 2). Data show GMFI ± SEM, n = 7 experiments/group with n = 2–4 male donors/experiment. *p<0.05, **p<0.01 and ***p<0.001, compared to corresponding control wt cells, Mann-Whitney test.