Table 1. Assessment and measurement of saccades, and OCT imaging of each NPC patient, and the respective means of the control group.
ID | Age [years] | NPC disability score | Peak velocity [°/s] (number of recorded saccades) 30° rightwards clinical score | 30° leftwards clinical score | 20° upwards clinical score | 20° downwards clinical score | Compensating corollary | Macular OCT | Peripapillary OCT | ||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | 26 | 8 | 315 (3) | 1 | 244 (1) | 1 | N.A. (0) | 3 | N.A. (0) | 3 | B, H | normal | normal |
2 | 18 | 11 | 218 (2) | 0 | 284 (6) | 0 | N.A. (0) | 2 | N.A. (0) | 1 | B | normal | N.A. |
3 | 43 | 11 | 233 (6) | 0 | 289 (5) | 0 | 66 (3) | 3 | N.A. (0) | 3 | B | normal | normal |
4 | 10 | 9 | 123 (4) | 0 | 110 (2) | 0 | 42 (1) | 2 | N.A. (0) | 2 | B | N.A. | N.A. |
5 | 7 | 5 | 268 (5) | 0 | 263 (5) | 0 | N.A. (0) | 2 | 359 (3) | 2 | B | N.A. | N.A. |
6 | 17 | 2 | 401 (6) | 0 | 456 (7) | 0 | 80 (3) | 2 | 105 (5) | 2 | E | normal | normal |
7 | 28 | 8 | 318 (4) | 0 | 383 (7) | 0 | 112 (1) | 2 | 53 (1) | 2 | B | normal | normal |
8 | 21 | 12 | 334 (7) | 0 | 351 (6) | 0 | 184 (1) | 2 | 63 (1) | 2 | H | normal | normal |
9 | 14 | N.A. | 318 (3) | 0 | 263 (3) | 1 | N.A. (0) | 3 | N.A. (0) | 2 | none | N.A. | N.A. |
10 | 8 | 6 | 393 (4) | 0 | 456 (2) | 0 | 401 (4) | 0 | 255 (4) | 0 | none | normal | normal |
11 | 18 | 8 | 0 | 0 | 2 | 3 | none | normal | normal | ||||
12 | 7 | N.A. | 0 | 0 | 2 | 3 | none | N.A. | N.A. | ||||
13 | 6 | N.A. | 1 | 1 | 3 | 3 | H | N.A. | N.A. | ||||
14 | 14 | N.A. | 0 | 0 | 3 | 1 | H | N.A. | N.A. | ||||
15 | 21 | N.A. | 0 | 0 | 0 | 1 | B | N.A. | N.A. | ||||
16 | 21 | 8 | 1 | 1 | 2 | 3 | none | N.A. | N.A. | ||||
17 | 20 | N.A. | 0 | 0 | 3 | 2 | B | N.A. | N.A. | ||||
18 | 19 | N.A. | 0 | 0 | 3 | 3 | B | N.A. | N.A. | ||||
Controls | 33 (SD 18) | N.A. | 459 (SD 67) [305–677] | 451 (SD 66) [259–645] | 404 (SD 74) [224–609] | 378 (SD 67) [216–554] | N.A. | normal | normal |
B = vertical eye movements were initiated by blinking, H = compensatory or defense head movements in vertical eye movements (either upwards, or downwards, or both), E = compensating horizontal eye movements when vertical eye movements were tested.
Clinical saccade testing: 0 = normal, 1 = slowed slightly, 2 = slowed a lot, 3 = not triggerable, 4 = not assessable.
SD = standard deviation.