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. 2021 Jun 4;16(6):e0252988. doi: 10.1371/journal.pone.0252988

Correction: Impact of disease stage and age at Parkinson’s onset on patients’ primary concerns: Insights for targeted management

Roongroj Bhidayasiri, Thanatat Boonmongkol, Yuwadee Thongchuam, Saisamorn Phumphid, Nitinan Kantachadvanich, Pattamon Panyakaew, Priya Jagota, Rachaneewan Plengsri, Marisa Chokpatcharavate, Onanong Phokaewvarangkul
PMCID: PMC8177543  PMID: 34086812

In the Introduction, there is an error in the last sentence of the second paragraph. The correct sentence is: A larger survey from Thailand found significant knowledge gaps amongst PD patients across three domains: diagnosis, therapeutic options, and disease course, suggesting the need for education.

There are errors in Table 1. Numerous values in the Results column are incorrect. Please see the correct Table 1 here.

Table 1. Demographics of the 222 PD patients who completed the Parkinson’s disease patients’ concerns survey.

Item Results
Age 67.69 ± 10.84
Male gender 125 (56.3%)
Disease duration 10.40 ± 6.58
Presenting symptoms at the time of diagnosis:
    ■ Bradykinesia 127 (61.7%)
    ■ Tremor 108 (48.6%)
    ■ Rigidity 93 (41.9%)
    ■ Gait difficulty 87 (39.2%)
Mean HY Score (all patients) 2.76 ± 0.91
Number at each HY stage:
    ■ Stage 1 6 (2.7%)
    ■ Stage 2 97 (43.7%)
    ■ Stage 3 73 (32.9%)
    ■ Stage 4 36 (16.2%)
    ■ Stage 5 10 (4.5%)
Presence of postural instability 119 (53.6%)
Presence of caregivers 112 (50.5%)
Categorical data are reported as number and percentage; continuous data are reported as mean ± standard deviation. HY: Hoehn & Yahr stage

There is an error in Table 5. In the second Overall severity column, the result for the symptom “Turning in bed” is missing. Please see the correct Table 5 here.

Table 5. Comparison of the most commonly concerning symptoms between young-onset and typical-onset PD patients on (a) motor symptoms, (b) non-motor symptoms, (c) symptom fluctuations, (d) adverse events, and (e) care in the advanced stage (n = 222).

Young-onset PD Typical-onset PD
Symptom (%) Overall severity Symptom (%) Overall severity
    a. Motor symptoms
Freezing of gait (46.3%) 5.37 ± 3.40 Getting out of bed (39.5%)
Problems with walking and/or balance (39.5%)
5.04 ± 3.10
5.31 ± 2.94
Problems with walking and/or balance (44.4%) 5.87 ± 2.91 Freezing of gait (33.5%) 4.77 ± 3.39
Difficulty speaking (42.6%) 5.65 ± 2.99 Turning in bed (29.3%) + 3.33
    b. Non-motor symptoms
Constipation (48.1%) 5.67 ± 3.19 Constipation (38.9%) 4.99 ± 3.46
Fatigue (31.5%) 4.81 ± 3.03 Fatigue (31.1%) 4.26 ± 2.97
Daytime sleepiness (27.8%)
Anxiety and/or panic attacks (27.8%)
4.22 ± 2.75
4.81 ± 2.50
Urinary problems (29.9%) 4.25 ± 3.22
    c. Symptom fluctuations
Slow movement (57.4%) 6.46 ± 2.62 Slow movement (36.5%) 4.80 ± 3.10
Difficulty performing fine finger movements (53.7%) 6.26 ± 2.72 Muscle cramping (31.7%)
Pain and/or aching (31.7%)
4.41 ± 3.13
4.66 ± 2.89
Any stiffness (50.0%)
Muscle cramping (50.0%)
5.76 ± 3.05
5.96 ± 2.75
Any stiffness (29.3%) 4.23 ± 3.13
    d. Adverse events
Gastrointestinal symptoms (37%) 4.72 ± 3.40 Gastrointestinal symptoms (29.9%) 4.47 ± 3.17
Urinary symptoms (31.5%) 4.35 ± 3.41 Urinary symptoms (21.6%) 3.84 ± 3.23
General symptoms (16.7%)
Neuropsychiatric symptoms (16.7%)
3.44 ± 2.85
3.33 ± 2.91
Neuropsychiatric symptoms (16.8%) 2.95 ± 2.98
    e. Care in the advanced stage
Marked decline in physical ability (53.7%) 6.63 ± 2.84 Marked decline in physical ability (35.9%) 5.01 ± 3.24
Bedridden/wheelchair bound (44.4%) 5.26 ± 4.05 Bedridden/wheelchair bound (31.7%) 4.18 ± 3.78
Difficulty swallowing (42.6%) 4.67 ± 3.61 Cognitive difficulties (28.1%) 3.95 ± 3.29
Severity scores are reported as mean ± standard deviation.

Reference

  • 1.Bhidayasiri R, Boonmongkol T, Thongchuam Y, Phumphid S, Kantachadvanich N, Panyakaew P, et al. (2020) Impact of disease stage and age at Parkinson’s onset on patients’ primary concerns: Insights for targeted management. PLoS ONE 15(12): e0243051. 10.1371/journal.pone.0243051 [DOI] [PMC free article] [PubMed] [Google Scholar]

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