In the Introduction, there is an error in the last sentence of the second paragraph. The correct sentence is: A larger survey from Thailand found significant knowledge gaps amongst PD patients across three domains: diagnosis, therapeutic options, and disease course, suggesting the need for education.
There are errors in Table 1. Numerous values in the Results column are incorrect. Please see the correct Table 1 here.
Table 1. Demographics of the 222 PD patients who completed the Parkinson’s disease patients’ concerns survey.
Item | Results |
---|---|
Age | 67.69 ± 10.84 |
Male gender | 125 (56.3%) |
Disease duration | 10.40 ± 6.58 |
Presenting symptoms at the time of diagnosis: | |
■ Bradykinesia | 127 (61.7%) |
■ Tremor | 108 (48.6%) |
■ Rigidity | 93 (41.9%) |
■ Gait difficulty | 87 (39.2%) |
Mean HY Score (all patients) | 2.76 ± 0.91 |
Number at each HY stage: | |
■ Stage 1 | 6 (2.7%) |
■ Stage 2 | 97 (43.7%) |
■ Stage 3 | 73 (32.9%) |
■ Stage 4 | 36 (16.2%) |
■ Stage 5 | 10 (4.5%) |
Presence of postural instability | 119 (53.6%) |
Presence of caregivers | 112 (50.5%) |
Categorical data are reported as number and percentage; continuous data are reported as mean ± standard deviation. HY: Hoehn & Yahr stage |
There is an error in Table 5. In the second Overall severity column, the result for the symptom “Turning in bed” is missing. Please see the correct Table 5 here.
Table 5. Comparison of the most commonly concerning symptoms between young-onset and typical-onset PD patients on (a) motor symptoms, (b) non-motor symptoms, (c) symptom fluctuations, (d) adverse events, and (e) care in the advanced stage (n = 222).
Young-onset PD | Typical-onset PD | ||
---|---|---|---|
Symptom (%) | Overall severity | Symptom (%) | Overall severity |
a. Motor symptoms | |||
Freezing of gait (46.3%) | 5.37 ± 3.40 | Getting out of bed (39.5%) Problems with walking and/or balance (39.5%) |
5.04 ± 3.10 5.31 ± 2.94 |
Problems with walking and/or balance (44.4%) | 5.87 ± 2.91 | Freezing of gait (33.5%) | 4.77 ± 3.39 |
Difficulty speaking (42.6%) | 5.65 ± 2.99 | Turning in bed (29.3%) | + 3.33 |
b. Non-motor symptoms | |||
Constipation (48.1%) | 5.67 ± 3.19 | Constipation (38.9%) | 4.99 ± 3.46 |
Fatigue (31.5%) | 4.81 ± 3.03 | Fatigue (31.1%) | 4.26 ± 2.97 |
Daytime sleepiness (27.8%) Anxiety and/or panic attacks (27.8%) |
4.22 ± 2.75 4.81 ± 2.50 |
Urinary problems (29.9%) | 4.25 ± 3.22 |
c. Symptom fluctuations | |||
Slow movement (57.4%) | 6.46 ± 2.62 | Slow movement (36.5%) | 4.80 ± 3.10 |
Difficulty performing fine finger movements (53.7%) | 6.26 ± 2.72 | Muscle cramping (31.7%) Pain and/or aching (31.7%) |
4.41 ± 3.13 4.66 ± 2.89 |
Any stiffness (50.0%) Muscle cramping (50.0%) |
5.76 ± 3.05 5.96 ± 2.75 |
Any stiffness (29.3%) | 4.23 ± 3.13 |
d. Adverse events | |||
Gastrointestinal symptoms (37%) | 4.72 ± 3.40 | Gastrointestinal symptoms (29.9%) | 4.47 ± 3.17 |
Urinary symptoms (31.5%) | 4.35 ± 3.41 | Urinary symptoms (21.6%) | 3.84 ± 3.23 |
General symptoms (16.7%) Neuropsychiatric symptoms (16.7%) |
3.44 ± 2.85 3.33 ± 2.91 |
Neuropsychiatric symptoms (16.8%) | 2.95 ± 2.98 |
e. Care in the advanced stage | |||
Marked decline in physical ability (53.7%) | 6.63 ± 2.84 | Marked decline in physical ability (35.9%) | 5.01 ± 3.24 |
Bedridden/wheelchair bound (44.4%) | 5.26 ± 4.05 | Bedridden/wheelchair bound (31.7%) | 4.18 ± 3.78 |
Difficulty swallowing (42.6%) | 4.67 ± 3.61 | Cognitive difficulties (28.1%) | 3.95 ± 3.29 |
Severity scores are reported as mean ± standard deviation. |
Reference
- 1.Bhidayasiri R, Boonmongkol T, Thongchuam Y, Phumphid S, Kantachadvanich N, Panyakaew P, et al. (2020) Impact of disease stage and age at Parkinson’s onset on patients’ primary concerns: Insights for targeted management. PLoS ONE 15(12): e0243051. 10.1371/journal.pone.0243051 [DOI] [PMC free article] [PubMed] [Google Scholar]