Table 2. LGM levels (mean ± SE) in individuals with healthy (n = 40) and unhealthy (n = 40) metabolic profiles in the pilot study.

LGMs	Individuals with healthy metabolic profiles	Individuals with unhealthy metabolic profiles	p-valuea
Zonulin (ng/mL)	37.8 (1.1)	48.8 (1.7)	<0.001
EndoCAb IgA (AMU/mL)	49.0 (14.0)	63.6 (15.9)	0.27
EndoCAb IgM (MMU/mL)	1.8 (0.07)	1.8 (0.04)	0.26
EndoCAb IgG (GMU/mL)	91.4 (11.5)	90.5 (11.4)	0.92
BPI (ng/mL)	2.3 (0.5)	6.1 (1.8)	0.02
PG (ng/mL)	1.3 (0.5)	2.6 (1.1)	0.04
LBP (μg/mL)	10.2 (0.7)	12.6 (0.7)	0.01
sCD14 (μg/mL)	1.2 (0.04)	1.4 (0.06)	0.01

^aSignificance by the Mann–Whitney U test (raw data were not normally distributed, as evaluated using the Shapiro–Wilk test).

BPI: bactericidal/permeability-increasing protein, LBP: LPS-binding protein, sCD14: soluble CD14, PG: peptidoglycan.