Appendix Figure A1.

Magnetic Resonance Imaging (MRI) and T2 relaxation times of different experimental groups: A) Sagittal MRI scan with T2 map overlay of the distal femur cartilage at 12 weeks after implantation of ascorbic acid and iron treated chondrogenic pellets (AF-MSCs, yellow arrows) and ascorbic acid, ferumoxytol and mitomycin-treated chondrogenic pellets (AFM-MSCs, red arrows). B) Sagittal MRI scan with T2 map overlay of the distal femur cartilage at 12 weeks after cartilage defect creation without any cell transplant (Untreated group, blue arrows). C) T2 relaxation times of the cartilage of different experimental groups and healthy adjacent cartilage at 12 weeks. All data are means ± SEM. Comparisons between different groups were obtained with Mann-Whitney test. A= Ascorbic acid, F= Ferumoxytol, M= Mitomycin.