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Treating Age-Related Macular Degeneration (AMD) with an aptamer. A: Macugen or VEGF antibodies target Vascular Endothelial Growth Factor (VEGF) that induces neovascularization and vision loss in AMD. B: Aptamer or antibody-based VEGF inhibitors are injected into the vitreous space to bind VEGF in the eye, prevent it from binding to its target receptor and thereby inhibit neovascularization, effectively treating AMD.
