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. Author manuscript; available in PMC: 2021 Jun 4.
Published in final edited form as: Semin Immunol. 2019 Jun;43:101299. doi: 10.1016/j.smim.2019.101299

Figure 3:

Figure 3:

Proposed model on the roles of classical immune checkpoints and putative “intracellular immune checkpoints” related to IFN-signaling pathways. IICs - Intracellular Immune Checkpoints, NC-ISPs - Non-Canonical IFN Signaling Pathways