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. 2021 May 2;112(6):2272–2286. doi: 10.1111/cas.14713

Table 1.

Association between SNP and lung cancer risks stratified by smoking status

SNP Effect/Other allele All (N = 1347) a Smoker (N = 735) b Non‐smoker (N = 612) c
OR (95% CI) P OR (95% CI) P OR (95% CI) P
rs10134980 C/A 0.91 (0.75,1.11) .36 0.84 (0.63,1.12) .23 1.05 (0.77,1.45) .75
rs1059292 T/C 0.98 (0.79,1.23) .89 1.18 (0.86,1.61) .30 0.74 (0.51,1.08) .12
rs11655237 C/T 1.08 (0.89,1.31) .42 1.15 (0.88,1.51) .30 0.90 (0.66,1.22) .48
rs1549334 G/A 0.98 (0.82,1.18) .84 1.09 (0.84,1.41) .52 0.79 (0.58,1.07) .13
rs2239895 G/C 1.13 (0.90,1.42) .28 1.06 (0.77,1.48) .71 1.38 (0.95,1.99) .09
rs2275159 G/A 1.02 (0.85,1.24) .82 1.11 (0.85,1.45) .44 0.89 (0.66,1.21) .45
rs2295441 T/C 0.99 (0.84,1.16) .88 0.98 (0.78,1.24) .87 1.04 (0.81,1.35) .74
rs2302177 T/G 1.04 (0.89,1.22) .61 1.10 (0.88,1.37) .41 0.92 (0.70,1.19) .51
rs2720660 G/A 0.96 (0.74,1.24) .75 0.97 (0.63,1.42) .87 0.80 (0.54,1.19) .28
rs28631713 G/A 1.17 (0.95,1.45) .14 1.10 (0.81,1.49) .55 1.24 (0.88,1.73) .22
rs3093873 T/C 1.10 (0.89,1.35) .38 1.12 (0.82,1.52) .48 0.95 (0.69,1.30) .73
rs3200401 T/C 1.10 (0.88,1.38) .39 0.90 (0.66,1.24) .53 1.19 (0.84,1.69) .34
rs3783358 G/C 1.16 (0.98,1.37) .09 1.19 (0.94,1.50) .15 1.12 (0.85,1.47) .43
rs3788632 T/C 0.99 (0.79,1.25) .94 1.13 (0.82,1.56) .45 0.90 (0.60,1.34) .60
rs3806357 G/A 0.96 (0.81,1.15) .69 0.87 (0.67,1.12) .27 1.15 (0.86,1.55) .35
rs4142441 G/A 1.18 (0.91,1.53) .22 0.79 (0.54,1.14) .21 1.71 (1.14,2.58) .01*

Abbreviations: CI, confidence interval; N, number of patients; OR, odds ratio; SNP, single‐nucleotide polymorphism.

a

Logistic regression adjusted for age, gender and smoking status (additive model).

b

Logistic regression adjusted for age and gender (additive model).

c

Logistic regression adjusted for age and gender (additive model).

*

Effective allele vs. other allele, 2‐tailed P‐value < .05.