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. 2021 May 2;112(6):2371–2380. doi: 10.1111/cas.14879

FIGURE 3.

FIGURE 3

Detection of NRAS‐Q61K mutation in osimertinib‐resistant case. A, NRAS Q61K was detected from the clinical samples from patient No. 24 with NGS. B, Cell viability assay using osimertinib‐resistant PC9 with NRAS Q61K showed that trametinib and osimertinib combination can overcome the resistance with NRAS Q61K mutation