TABLE 1.
Baseline characteristics of cancer cases and controls
| Characteristics |
Cases (n = 601 733) |
Controls (n = 2 406 932) |
P‐value |
|---|---|---|---|
| Age a | 1 | ||
| Mean (SD) | 60.47 (15.37) | 60.47 (15.37) | |
| Gender b | 1 | ||
| Male (%) | 324 710 (53.96) | 1 298 840 (53.96) | |
| Comorbid conditions, N (%) | |||
| Myocardial infarction | 9920 (1.65) | 37 873 (1.57) | <.0001 |
| Congestive heart failure | 45 691 (7.59) | 157 383 (6.54) | <.0001 |
| Peripheral vascular disease | 21 132 (3.51) | 84 259 (3.50) | .502 |
| Cerebrovascular disease | 99 179 (16.48) | 377 753 (15.69) | <.0001 |
| Dementia | 17 898 (2.97) | 76 309 (3.17) | <.0001 |
| COPD | 148 277 (24.64) | 529 501 (22.00) | <.0001 |
| Rheumatic disease | 24 504 (4.07) | 94 513 (3.93) | <.0001 |
| Peptic ulcer disease | 893 550 (37.12) | <.0001 | |
| Liver disease | 175 036 (29.09) | 504 462 (20.96) | <.0001 |
| Diabetes | 143 890 (23.91) | 514 572 (21.38) | <.0001 |
| Hemiplegia or paraplegia | 6688 (1.11) | 27 754 (1.15) | <.0001 |
| Renal disease | 55 358 (9.20) | 176 645 (7.34) | <.0001 |
| Age‐adjusted CCI scores | <.0001 | ||
| Mean (SD) | 3.58 (2.68) | 3.31 (2.57) | |
| Other drugs, N (%) | |||
| Aspirin | 88 153 (14.65) | 353 001 (14.67) | .599 |
| Statins | 66 975 (11.13) | 264 605 (10.99) | <.0001 |
| ACEI/ARB | 131 636 (21.88) | 513 058 (21.32) | <.0001 |
ACEI/ARB, angiotensin‐converting enzyme inhibitors/angiotensin II receptor blockers; CCI, Charlson comorbidities index; COPD, chronic obstructive pulmonary disease; SD, standard deviation.
a
The continuous variables were compared using paired t‐tests.
b
The categorical variables were compared using the McNemar test.