Skip to main content
. 2021 Apr 16;7(2):185–198.

Table 6. Results of Studies Combining Chemoradiotherapy with Immunotherapy in Stage III NSCLC.

n Intervention DFS OS (%) Toxicity>Grade 3 (%)
PACIFIC [6,117] 714 CRT (54–66 Gy)→Durvalumab. Median, 18.8 months 1 year: 83.1 2 year: 66.3 30.5
LUN 14-179 [119] 92 CRT (59.4–66 Gy)→Pembrolizumab. Median, 15.4 months 1 year: 80.5 2 year: 68.7 6.5
ETOP NICOLAS [121,125] 80 CRT (66 Gy)+Nivolumab→Nivolumab 1 year 1 year: 54% 1 year: 79 10.9
DETERRED [120] 40 Part 1: CRT (60–66 Gy)→CT+Atezolizumab×2 cycles→Atezolizumab 1 year Part 2: CRT (60–66 Gy)+Atezolizumab→CT+Atezolizumab×2 cycles→Atezolizumab 1 year 1 year: 57% 1 year: 79 27.5

DFS: Disease-free survival, OS: Overall survival, CRT: Chemoradiotherapy, CT: Chemotherapy