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. 2021 Jun 5;2:100035. doi: 10.1016/j.crphar.2021.100035

Figure 1.

Figure 1

Possible mechanisms involved in the olfactory dysfunction (anosmia) in patients with COVID-19. After contact with droplets containing viral particles from an infected patient, the virus penetrates the nasal cavity reaching the receptors for smell and the olfactory nerve, which characterizes the transneural pathway. On the other hand, the virus might reach these structures through the hematogenous route or by breaking the blood-brain barrier.