Table 11.
Renal MDA and GSH concentrations of Cnidoscolus aconitifolius and ascorbate treatments in DMN-induced toxicity.
| Group | MDA (nM) | GSH (μg/mL) |
|---|---|---|
| Control | 23.87 ± 3.62abcd | 11.75 ± 0.11abc |
| 200 CA | 22.42 ± 5.88abc | 12.68 ± 0.60bcd |
| 400 CA | 18.84 ± 2.85ab | 12.34 ± 0.26bc |
| 400 VitC | 24.52 ± 1.83abcd | 12.81 ± 0.14bcd |
| DMN | 53.39 ± 4.31f | 10.52 ± 0.43a |
| DMN + 200 CA | 49.68 ± 7.27ef | 12.25 ± 0.27bc |
| 200 CA + DMN | 40.64 ± 7.11cdef | 12.65 ± 0.62bcd |
| DMN + 400 CA | 33.33 ± 7.54bcde | 11.80 ± 0.19bc |
| 400 CA + DMN | 41.08 ± 11.31def | 12.30 ± 0.12bc |
| DMN + 400 ASC | 33.88 ± 11.94bcde | 12.62 ± 0.32bcd |
| 400 ASC + DMN | 26.88 ± 5.53abcd | 12.94 ± 0.25cd |
Values are expressed as mean ± SEM; n = 5. Values with different superscript along the same column are statistically significant (p values < 0.05). DMN = dimethyl nitrosamine; CA =Cnidoscolus aconitifolius; ASC = Ascorbate.