Table 2.
Concordant T− (n = 99) | Concordant T+ (n = 107) | Discordant T status (n = 145) | p value* | |
---|---|---|---|---|
Age | 68.1 ± 8.3 | 68.4 ± 9.3 | 73.7 ± 8.5 | p < .001† |
Sex (M, %) | 39 (39%) | 39 (36%) | 78 (54%) | p = .01 |
Education | 15.6 ± 3.9 | 15.4 ± 3.3 | 15.5 ± 3.6 | p = .83 |
MMSE | 28.3 ± 2.5 | 23.2 ± 5.0 | 26.9 ± 4.6 | p <.001† |
Amyloid status (Aβ+, %) | 14 (14%) | 106 (99%) | 76 (52%) | p <.001 |
CSF PTau181 (pg/mL) | 16.1 ± 4.2 | 42.4 ± 16.6 | 23.2 ± 8.5 | p <.001 |
FTP SUVR | 1.14 ± 0.1 | 1.97 ± 0.5 | 1.28 ± 0.3 | p < .001 |
Diagnosis (% Aβ+) | 52 CN (15%) | 9 CN (89%) | 66 CN (48%) | p < .001 |
23 MCI (17%) | 38 MCI (100%) | 45 MCI (42%) | ||
2 ADc (0%) | 59 ADc (100%) | 23 ADc (96%) | ||
22 non–AD (9%) | 1 non-AD (100%) | 11 non-AD (27%) |
p values shown for Kruskal-Wallis H test for continuous variables, and x2 for nominal variables
Bonferroni-corrected p values for pairwise comparisons are all < .001 except; T− vs discordant T for age (p = 1.0), and T– vs discordant T for MMSE (p = .06)